It won't hurt your Fusion, however, many cars will see a loss of fuel economy on the E10 fuel. My fathers Lincoln LS looses 3 MPG on E10 and a friend has a 05 Mountaineer and it losses 2.5 MPG on E10, I've seen many other cars that had no effect on fuel economy, but I'd guess that on average you loose 1 MPG. Run 3 tanks of each back to back and see what you get for mileage.
Also I recomend running some fuel line anti-Freeze (heat or any Isopropyl) to keep the water out of the fuel tank that for some reason Ethanol seems to have more of than regular fuel. You only need to do this every couple of months at most, many cars never have any problems, but we do see a noticible number (2-3%) that will develop hard start or start then die concerncs caused by this (but a bottle of additive fixes them up in 1 tank of fuel)